In vitro susceptibilities of isolates of Sporothrix schenckii to itraconazole and terbinafine.
نویسندگان
چکیده
Thirty isolates of the yeast form of Sporothrix schenckii were evaluated for in vitro susceptibility to itraconazole and terbinafine by the recommended NCCLS modified technique (M27-A2). The MICs of itraconazole obtained oscillated between 0.062 and 4.0 microg/ml, and those of terbinafine oscillated between 0.007 and 0.50 microg/ml; therefore, terbinafine showed greater in vitro activity.
منابع مشابه
[In vitro susceptibility of isolates of Sporothrix schenckii to terbinafine and itraconazole].
The study objective was to determine the in vitro activity of terbinafine and itraconazole through the microdilution technique in broth (NCCLSM27-A2), adapted for dimorphic fungus, in relation to 12 isolates of Sporothrix schenckii. Six were from feline sporotrichosis, three from human sporotrichosis, one from a dog and two from human isolates originating from Instituto Oswaldo Cruz. The inocul...
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ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 42 9 شماره
صفحات -
تاریخ انتشار 2004