In vitro susceptibilities of isolates of Sporothrix schenckii to itraconazole and terbinafine.

نویسندگان

  • Lidiane Meire Kohler
  • Paulo César Fialho Monteiro
  • Rosane Christine Hahn
  • Júnia Soares Hamdan
چکیده

Thirty isolates of the yeast form of Sporothrix schenckii were evaluated for in vitro susceptibility to itraconazole and terbinafine by the recommended NCCLS modified technique (M27-A2). The MICs of itraconazole obtained oscillated between 0.062 and 4.0 microg/ml, and those of terbinafine oscillated between 0.007 and 0.50 microg/ml; therefore, terbinafine showed greater in vitro activity.

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منابع مشابه

[In vitro susceptibility of isolates of Sporothrix schenckii to terbinafine and itraconazole].

The study objective was to determine the in vitro activity of terbinafine and itraconazole through the microdilution technique in broth (NCCLSM27-A2), adapted for dimorphic fungus, in relation to 12 isolates of Sporothrix schenckii. Six were from feline sporotrichosis, three from human sporotrichosis, one from a dog and two from human isolates originating from Instituto Oswaldo Cruz. The inocul...

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Sporothrix schenckii associated with armadillo hunting in Southern Brazil: epidemiological and antifungal susceptibility profiles Sporothrix schenckii relacionado à caça ao tatu no Sul do Brasil: aspectos epidemiológicos e suscetibilidade dos isolados aos antifúngicos

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 42 9  شماره 

صفحات  -

تاریخ انتشار 2004